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Study: Gum infection and Alzheimer’s are linked

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Brain in Alzheimer’s disease

Alzheimer’s, a disease without cure, has been found linked to gum infection. A study recently conducted suggests that bacteria Porphyromonas Gingivalis, one responsible for destroying gum tissue, has deep links to Alzheimer’s.

There are both good and bad news here: the good being that the drugs that can block the bacteria Porphyromonas Gingivalis are entering clinical trials this year and also there could be a vaccine. The bad here is that around 1/3 of all the people in the world have gun infections, meaning that their changes of getting Alzheimer’s are far higher.

According to the study, researchers observed the bacteria in the brains of Alzheimer patients and also conducted mice tests. The results revealed that gum infection led to an increase in production of Amyloid Beta — the one responsible for amyloid plaques in Alzheimer patients.

Casey Lynch, one of the researchers and CEO of Cortexyme, said that despite the funding and best efforts, clinical progress against Alzheimer’s has been frustratingly slow.

The gum disease bacteria was also found in the brains of people with no Alzheimer’s, at far lower levels. Researchers believe that Alzheimer hits people that develop gingipains and damage to their brains fast enough — this could be the cause, but it’s not a final result.

James Pickett, head of research at Alzheimer’s Society, said in a statement that they had supported to uncover key causes behind Alzheimer’s and gum disease has not been a major cause for concern.

One in ten people at the age of 65 and older, gets infected with Alzheimer’s. It’s one of the most common and deadly diseases but still no cure. With this new foundation, maybe a vaccine for gum diseases might be able to stop this deadly disease.